Albino Swiss rats are used in toxicology and pharmacology studies. This strain is relatively susceptible to atherosclerosis. Aged mice show a high prevalence of breast and lung tumors. With increasing age, they suffer from polydipsia and polyuria caused by nephrogenic diabetes. This strain is useful for the production of transgenic mice because they are highly responsive to exogenous hormones. The Swiss Outbred mouse is a versatile inbred mouse used in all areas of biomedical research (general studies), used as embryo donor and/or recipient.