DBA/2J are not very sensitive to the development of atherosclerotic lesions. It shows hearing loss of high frequencies starting at weaning (3-4 weeks).This hearing loss become sever by 2-3 months of age. Young DBA/2J inbred mice are susceptible to the audiogenic seizures. This strain also presents high rates of calcareous pericarditis, calcified lesions of the testicles, tongue and muscles.DBA/2 mice develop progressive eye disease similar to human hereditary glaucoma.