BALB/CJ
Strain Name : BALB/cJRj
Type : SPF:Inbred mouse
Colour and related genotype : Albino mouse
Breeding : Difficult to rear
BALB/c is a type of albino and Inbred laboratory mouse. BALB/c mice are particularly well known for the production of plasmacytomas following injection with mineral oil forming the basis for the production of monoclonal antibodies.BALB/c mice develop breast cancer rarely, but other cancers, including reticular neoplasms, primary lung tumors, and renal tumors are prevalent. BALB/c strains are susceptible to Listeria, all species of Leishmania, and several species of trypanosome.
Main Application And Research Fields
- Cardiovascular research
- Immunology: ascites production, monoclonal antibodies
- Inflammation
- Neurology
- Oncology
- Parasitology
- Virology
| Hematological parameters* of 10-week old BALB/cJRj mice | ||
|---|---|---|
| Parameters | Male | Female |
| Erythrocytes (1012/l) | 10.3 ± 0.7 | 10.4 ± 0.5 |
| Hematocrit (l/l) | 0.57 ± 0.03 | 0.57 ± 0.03 |
| Hemoglobin (g/dl) | 15.5 ± 0.7 | 16.0 ± 0.8 |
| Mean corpuscular volume (fl) | 55 ± 1 | 56 ± 1 |
| Mean corpuscular rate (pg) | 15.3 ± 0.5 | 15.5 ± 0.5 |
| Hemoglobin concentration (g/dl) | 27 ± 1 | 28 ± 1 |
| Blood platelets (109/l) | 735 ± 188 | 621 ± 275 |
| Leukocytes (109/l) | 5.1 ± 2.3 | 5.1 ± 2.0 |
| Neutrophils (109/l) | 1.22 ± 0.37 | 1.28 ± 0.39 |
| Lymphocytes (109/l) | 3.83 ± 1.95 | 3.62 ± 1.57 |
| Eosinophils (109/l) | 0.20 ± 0.06 | 0.16 ± 0.07 |
| Monocytes (109/l) | 0.05 ± 0.02 | 0.06 ± 0.03 |
| Basophils (109/l) | 0.03 ± 0.04 | 0.02 ± 0.03 |
| Biochemical blood parameters* of 10-week old BALB/cJRj mice | ||
|---|---|---|
| Parameters | Male | Female |
| Glucose (g/l) | 2.1 ± 0.3 | 2.1 ± 0.3 |
| Urea (g/l) | 0.6 ± 0.1 | 0.8 ± 0.1 |
| AST (ASAT) (UI/l) | 170 ± 50 | 233 ± 124 |
| ALT (ALAT) (UI/l) | 58 ± 17 | 74 ± 52 |
| Alkaline phosphatase (UI/l) | 194 ± 32 | 204 ± 48 |
| Cholesterolaemia (g/l) | 1.5 ± 0.3 | 1.1 ± 0.2 |
| Triglycerides (g/l) | 1.5 ± 0.5 | 1.9 ± 0.8 |
| Creatinine (mg/l) | 5.1 ± 0.4 | 5.2 ± 0.6 |
| Reproductive data* | |
|---|---|
| Bigamous mating | |
| Litter size at birth | 5.8 |
| Weaning % | 91 |
| Productivity index | 0.79 |
| Sterility % | 2 |
| Gestation time | Between 18 and 20 days |
